AUTONOMIC INNERVATION OF THE CILIARY BODY



Sympathetic nerves have been located histologically in the
ciliary body interstitium, near to the double epithelia.
We hypothesize that this could produce high enough levels
of norepinephrine (NE on the cartoon) to reach the stimulatory
range that we demonstrated in the NPE tissue culture.

Ludwig et al (J. Neru. Trans (1990) Supp32:441) argue by
clearnce studies that synaptic cleft norepinephrine (NE, although
in the Ludwig paper, the english designation for the hormone,
noradrenaline (NA) is used) is 3.6 times greater that plasma
levels. This, however, represents an average across active and
inactive synapes. The authors also admit possible sources of
error arising from baroceptor and reuptake mechanisms.

Marianne Fillenz (;Harwood
Academic Publishers;1992;Ch.6, "Transmission: Noradrenaline;" p328)
gives norepinephine concentrations in the large and small terminal
vesicles of 120-220mM and 36-60mM respectively.

Weltman et al (A. J. Phys. 76(3):1144;1994) give an
plasma levels of 820+-127pg/ml NE during rowing and
1712+-217pg/ml during running.


Say hello?
Favorite Places on the Web.